Leucocytosis after Amoxicillin in dogs

102 reports to the FDA describe leucocytosis in dogs given Amoxicillin. That is 7.6% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

102Reports

75%Marked serious

3.9%Recovered

47%Died or euthanised

5 daysTypical onset

How soon it started

Same day

15 21%

1–2 days

16 22%

3–7 days

15 21%

1–4 weeks

16 22%

Over a month

11 15%

How the animals did

Recovered

4 3.9%

Still unwell when reported

26 25%

Died

16 16%

Euthanised

32 31%

Not known

24 24%

Problems reported at the same time

69 68%

66 65%

59 58%

54 53%

48 47%

46 45%

40 39%

38 37%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause leucocytosis in dogs?: 102 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

Leucocytosis after Amoxicillin + Clavulanate (Clavamox) 349 reports · 6.5% of its reports
Leucocytosis after Doxycycline 210 reports · 5.2% of its reports
Leucocytosis after Cefovecin (Convenia) 175 reports · 4.6% of its reports
Leucocytosis after Enrofloxacin (Baytril) 222 reports · 5.9% of its reports
Leucocytosis after Metronidazole 199 reports · 6.4% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with leucocytosis