Neutrophilia after Amoxicillin in dogs

67 reports to the FDA describe neutrophilia in dogs given Amoxicillin. That is 5.0% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

67Reports

82%Marked serious

6.0%Recovered

42%Died or euthanised

5 daysTypical onset

How soon it started

Same day

8 17%

1–2 days

7 15%

3–7 days

13 28%

1–4 weeks

12 26%

Over a month

7 15%

How the animals did

Recovered

4 6.0%

Still unwell when reported

18 27%

Died

8 12%

Euthanised

20 30%

Not known

17 25%

Problems reported at the same time

48 72%

47 70%

46 69%

37 55%

32 48%

28 42%

27 40%

23 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause neutrophilia in dogs?: 67 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

Neutrophilia after Amoxicillin + Clavulanate (Clavamox) 231 reports · 4.3% of its reports
Neutrophilia after Doxycycline 165 reports · 4.1% of its reports
Neutrophilia after Cefovecin (Convenia) 111 reports · 2.9% of its reports
Neutrophilia after Enrofloxacin (Baytril) 156 reports · 4.1% of its reports
Neutrophilia after Metronidazole 168 reports · 5.4% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with neutrophilia