Kidney problems after Metronidazole in dogs

The FDA has received 337 reports of kidney problems in dogs after Metronidazole. That is 11% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

337Reports
83%Marked serious
7.4%Recovered
48%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
48 18%
1–2 days
47 17%
3–7 days
37 14%
1–4 weeks
58 21%
Over a month
81 30%

How the animals did

Recovered
21 6.2%
Recovered with lasting effects
4 1.2%
Still unwell when reported
120 36%
Died
52 15%
Euthanised
109 32%
Not known
31 9.2%

Problems reported at the same time

Age of the animals

Under 1 year
28
1–3 years
44
4–7 years
55
8–11 years
95
12+ years
114

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause kidney problems in dogs?
337 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Metronidazole in dogs · Medicines most reported with kidney problems