Seizures after Doxycycline in dogs

The FDA has received 185 reports of seizures in dogs after Doxycycline. That is 4.6% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

185Reports

93%Marked serious

21%Recovered

32%Died or euthanised

8 daysTypical onset

How soon it started

Same day

24 16%

1–2 days

21 14%

3–7 days

27 18%

1–4 weeks

41 27%

Over a month

40 26%

How the animals did

Recovered

37 20%

Recovered with lasting effects

2 1.1%

Still unwell when reported

52 28%

Died

30 16%

Euthanised

30 16%

Not known

34 18%

Problems reported at the same time

60 32%

39 21%

37 20%

35 19%

33 18%

28 15%

28 15%

25 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause seizures in dogs?: 185 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Amoxicillin + Clavulanate (Clavamox) 319 reports · 5.9% of its reports
Seizures after Cefovecin (Convenia) 264 reports · 7.0% of its reports
Seizures after Enrofloxacin (Baytril) 373 reports · 9.9% of its reports
Seizures after Metronidazole 172 reports · 5.6% of its reports
Seizures after Amoxicillin 88 reports · 6.5% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with seizures