Seizures after Amoxicillin in dogs

The FDA has received 88 reports of seizures in dogs after Amoxicillin. That is 6.5% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

88Reports

82%Marked serious

18%Recovered

33%Died or euthanised

9 daysTypical onset

How soon it started

Same day

7 11%

1–2 days

15 24%

3–7 days

7 11%

1–4 weeks

18 29%

Over a month

15 24%

How the animals did

Recovered

15 17%

Recovered with lasting effects

1 1.1%

Still unwell when reported

25 28%

Died

15 17%

Euthanised

14 16%

Not known

18 20%

Problems reported at the same time

27 31%

25 28%

22 25%

17 19%

16 18%

13 15%

13 15%

12 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause seizures in dogs?: 88 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Amoxicillin + Clavulanate (Clavamox) 319 reports · 5.9% of its reports
Seizures after Doxycycline 185 reports · 4.6% of its reports
Seizures after Cefovecin (Convenia) 264 reports · 7.0% of its reports
Seizures after Enrofloxacin (Baytril) 373 reports · 9.9% of its reports
Seizures after Metronidazole 172 reports · 5.6% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with seizures