Abnormal radiograph finding after Doxycycline in dogs

The FDA has received 206 reports of abnormal radiograph finding in dogs after Doxycycline. That is 5.1% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

206Reports

83%Marked serious

4.9%Recovered

33%Died or euthanised

23 daysTypical onset

How soon it started

Same day

19 12%

1–2 days

11 6.9%

3–7 days

25 16%

1–4 weeks

34 21%

Over a month

70 44%

How the animals did

Recovered

10 4.9%

Still unwell when reported

92 45%

Died

25 12%

Euthanised

44 21%

Not known

35 17%

Problems reported at the same time

91 44%

80 39%

79 38%

71 34%

69 33%

65 32%

63 31%

54 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause abnormal radiograph finding in dogs?: 206 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

Abnormal radiograph finding after Amoxicillin + Clavulanate (Clavamox) 274 reports · 5.1% of its reports
Abnormal radiograph finding after Cefovecin (Convenia) 151 reports · 4.0% of its reports
Abnormal radiograph finding after Enrofloxacin (Baytril) 178 reports · 4.7% of its reports
Abnormal radiograph finding after Metronidazole 173 reports · 5.6% of its reports
Abnormal radiograph finding after Amoxicillin 74 reports · 5.5% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with abnormal radiograph finding