Abnormal radiograph finding after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 274 reports of abnormal radiograph finding in dogs after Amoxicillin + Clavulanate. That is 5.1% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

274Reports

56%Marked serious

6.9%Recovered

37%Died or euthanised

8 daysTypical onset

How soon it started

Same day

28 16%

1–2 days

21 12%

3–7 days

37 21%

1–4 weeks

32 18%

Over a month

56 32%

How the animals did

Recovered

18 6.6%

Recovered with lasting effects

1 0.4%

Still unwell when reported

84 31%

Died

54 20%

Euthanised

48 18%

Not known

69 25%

Problems reported at the same time

132 48%

108 39%

105 38%

101 37%

98 36%

80 29%

75 27%

Didn't work as expected

68 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause abnormal radiograph finding in dogs?: 274 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

Abnormal radiograph finding after Doxycycline 206 reports · 5.1% of its reports
Abnormal radiograph finding after Cefovecin (Convenia) 151 reports · 4.0% of its reports
Abnormal radiograph finding after Enrofloxacin (Baytril) 178 reports · 4.7% of its reports
Abnormal radiograph finding after Metronidazole 173 reports · 5.6% of its reports
Abnormal radiograph finding after Amoxicillin 74 reports · 5.5% of its reports

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with abnormal radiograph finding