Loss of appetite after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 1,195 reports of loss of appetite in dogs after Amoxicillin + Clavulanate. That is 22% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,195Reports
49%Marked serious
10%Recovered
27%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
115 15%
1–2 days
149 19%
3–7 days
155 20%
1–4 weeks
176 23%
Over a month
175 23%

How the animals did

Recovered
118 9.9%
Recovered with lasting effects
7 0.6%
Still unwell when reported
396 33%
Died
178 15%
Euthanised
149 12%
Not known
347 29%

Problems reported at the same time

590 49%
535 45%
323 27%
226 19%

Age of the animals

Under 1 year
129
1–3 years
160
4–7 years
272
8–11 years
353
12+ years
255

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause loss of appetite in dogs?
1,195 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with loss of appetite