Death after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 830 reports of death in dogs after Amoxicillin + Clavulanate. That is 15% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

830Reports
66%Marked serious
0.0%Recovered
99%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
72 15%
1–2 days
88 18%
3–7 days
90 19%
1–4 weeks
128 26%
Over a month
106 22%

How the animals did

Died
524 63%
Euthanised
298 36%
Not known
8 1.0%

Problems reported at the same time

Age of the animals

Under 1 year
125
1–3 years
72
4–7 years
139
8–11 years
265
12+ years
209

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause death in dogs?
830 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with death