Not drinking after Diphenhydramine in dogs

68 reports to the FDA describe not drinking in dogs given Diphenhydramine. That is 1.4% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

68Reports
72%Marked serious
16%Recovered
24%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
23 40%
1–2 days
15 26%
3–7 days
6 10%
1–4 weeks
4 6.9%
Over a month
10 17%

How the animals did

Recovered
9 13%
Recovered with lasting effects
2 2.9%
Still unwell when reported
27 40%
Died
6 8.8%
Euthanised
10 15%
Not known
14 21%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
11
4–7 years
23
8–11 years
14
12+ years
11

About this medicine

Type: medicine.

Questions owners ask

Can Diphenhydramine cause not drinking in dogs?
68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not drinking with similar medicines

All reported side effects of Diphenhydramine in dogs · Medicines most reported with not drinking