Sedation after Dexmedetomidine (Dexdomitor) in dogs

235 reports to the FDA describe sedation in dogs given Dexmedetomidine. That is 4.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

235Reports
32%Marked serious
54%Recovered
3.8%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
157 89%
1–2 days
7 4.0%
3–7 days
1 0.6%
1–4 weeks
6 3.4%
Over a month
5 2.8%

How the animals did

Recovered
125 53%
Recovered with lasting effects
2 0.9%
Still unwell when reported
69 29%
Died
6 2.6%
Euthanised
3 1.3%
Not known
30 13%

Problems reported at the same time

Age of the animals

Under 1 year
18
1–3 years
40
4–7 years
54
8–11 years
59
12+ years
27

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause sedation in dogs?
235 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Sedation with similar medicines

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with sedation