Vomiting after Dexmedetomidine (Dexdomitor) in dogs

The FDA has received 588 reports of vomiting in dogs after Dexmedetomidine. That is 11% of all reports for this medicine, compared with 28% across reports for all dog medicines, so it is reported less often than average with this medicine.

588Reports

55%Marked serious

31%Recovered

19%Died or euthanised

1 daysTypical onset

How soon it started

Same day

199 42%

1–2 days

113 24%

3–7 days

54 12%

1–4 weeks

46 9.8%

Over a month

57 12%

How the animals did

Recovered

182 31%

Recovered with lasting effects

2 0.3%

Still unwell when reported

177 30%

Died

56 9.5%

Euthanised

56 9.5%

Not known

115 20%

Problems reported at the same time

256 44%

210 36%

195 33%

146 25%

106 18%

90 15%

Didn't work as expected

72 12%

Breathing problems

70 12%

Age of the animals

Under 1 year

1–3 years

141

4–7 years

222

8–11 years

118

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause vomiting in dogs?: 588 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Buprenorphine 383 reports · 24% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with vomiting