Dexmedetomidine (Dexdomitor) side effects in dogs

5,470 reports sent to the FDA between 2007 and 2026 involve Dexmedetomidine in dogs. The most reported problems were bradycardia, vomiting, loss of appetite. 43% were marked serious, and where it was recorded, signs eased after stopping the medicine in 87% of cases.

5,470Reports
43%Marked serious
37%Only medicine involved
39%Recovered
13%Died or euthanised
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About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
13 0.2%
Didn't stop worms
10 0.2%
Didn't stop ticks
2 0.0%
Didn't stop fleas
1 0.0%

How soon problems started

Same day
2,648 69%
1–2 days
429 11%
3–7 days
251 6.6%
1–4 weeks
262 6.8%
Over a month
238 6.2%

Time from the first dose to the first sign, where both dates were reported (3,828 reports).

How the animals did

Recovered
2,108 39%
Recovered with lasting effects
13 0.2%
Still unwell when reported
1,048 19%
Died
524 9.6%
Euthanised
172 3.1%
Not known
1,605 29%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other sedative or anaesthetics for dogs