Seizures after Dexmedetomidine (Dexdomitor) in dogs

335 reports to the FDA describe seizures in dogs given Dexmedetomidine. That is 6.1% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

335Reports

70%Marked serious

45%Recovered

19%Died or euthanised

Same dayTypical onset

How soon it started

Same day

183 74%

1–2 days

24 9.7%

3–7 days

14 5.6%

1–4 weeks

18 7.3%

Over a month

9 3.6%

How the animals did

Recovered

151 45%

Still unwell when reported

49 15%

Died

40 12%

Euthanised

24 7.2%

Not known

71 21%

Problems reported at the same time

62 19%

33 9.9%

30 9.0%

23 6.9%

23 6.9%

21 6.3%

20 6.0%

18 5.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

108

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause seizures in dogs?: 335 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Buprenorphine 109 reports · 6.9% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with seizures