Tremors after Dexmedetomidine (Dexdomitor) in dogs

The FDA has received 159 reports of tremors in dogs after Dexmedetomidine. That is 2.9% of all reports for this medicine, compared with 3.4% across reports for all dog medicines.

159Reports

53%Marked serious

33%Recovered

11%Died or euthanised

Same dayTypical onset

How soon it started

Same day

69 57%

1–2 days

22 18%

3–7 days

14 11%

1–4 weeks

11 9.0%

Over a month

6 4.9%

How the animals did

Recovered

53 33%

Still unwell when reported

47 30%

Died

5 3.1%

Euthanised

12 7.5%

Not known

42 26%

Problems reported at the same time

40 25%

38 24%

33 21%

32 20%

27 17%

24 15%

Didn't work as expected

18 11%

Death

17 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause tremors in dogs?: 159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Buprenorphine 76 reports · 4.8% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with tremors