Buprenorphine side effects in dogs

1,585 reports sent to the FDA between 2005 and 2026 involve Buprenorphine in dogs. The most reported problems were loss of appetite, vomiting, lethargy. 67% were marked serious, and where it was recorded, signs eased after stopping the medicine in 53% of cases.

1,585Reports
67%Marked serious
3.0%Only medicine involved
28%Recovered
24%Died or euthanised
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About this medicine

Buprenorphine pain relief (an opioid).

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
5 0.3%
Didn't stop fleas
1 0.1%

How soon problems started

Same day
650 46%
1–2 days
259 18%
3–7 days
149 10%
1–4 weeks
178 13%
Over a month
186 13%

Time from the first dose to the first sign, where both dates were reported (1,422 reports).

How the animals did

Recovered
436 28%
Recovered with lasting effects
11 0.7%
Still unwell when reported
513 32%
Died
193 12%
Euthanised
193 12%
Not known
239 15%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other sedative or anaesthetics for dogs