Pain after Buprenorphine in dogs

121 reports to the FDA describe pain in dogs given Buprenorphine. That is 7.6% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

121Reports

78%Marked serious

15%Recovered

21%Died or euthanised

1 daysTypical onset

How soon it started

Same day

49 44%

1–2 days

21 19%

3–7 days

10 8.9%

1–4 weeks

18 16%

Over a month

14 13%

How the animals did

Recovered

16 13%

Recovered with lasting effects

2 1.7%

Still unwell when reported

52 43%

Died

13 11%

Euthanised

13 11%

Not known

25 21%

Problems reported at the same time

57 47%

51 42%

44 36%

34 28%

Injection site reaction

34 28%

Breathing problems

30 25%

Swelling

30 25%

Death

26 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause pain in dogs?: 121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Dexmedetomidine (Dexdomitor) 142 reports · 2.6% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with pain