Vocalising after Buprenorphine in dogs

The FDA has received 157 reports of vocalising in dogs after Buprenorphine. That is 9.9% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports

69%Marked serious

25%Recovered

22%Died or euthanised

Same dayTypical onset

How soon it started

Same day

85 59%

1–2 days

18 13%

3–7 days

12 8.4%

1–4 weeks

12 8.4%

Over a month

16 11%

How the animals did

Recovered

37 24%

Recovered with lasting effects

2 1.3%

Still unwell when reported

51 32%

Died

17 11%

Euthanised

17 11%

Not known

33 21%

Problems reported at the same time

53 34%

51 32%

41 26%

36 23%

Injection site reaction

35 22%

Death

34 22%

Breathing problems

33 21%

Diarrhea

31 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause vocalising in dogs?: 157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Dexmedetomidine (Dexdomitor) 156 reports · 2.9% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with vocalising