Vocalising after Dexmedetomidine (Dexdomitor) in dogs

156 reports to the FDA describe vocalising in dogs given Dexmedetomidine. That is 2.9% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

156Reports

53%Marked serious

27%Recovered

15%Died or euthanised

Same dayTypical onset

How soon it started

Same day

82 65%

1–2 days

20 16%

3–7 days

6 4.8%

1–4 weeks

10 7.9%

Over a month

8 6.3%

How the animals did

Recovered

42 27%

Still unwell when reported

39 25%

Died

12 7.7%

Euthanised

12 7.7%

Not known

51 33%

Problems reported at the same time

Loss of appetite

38 24%

Injection site reaction

29 19%

28 18%

27 17%

27 17%

27 17%

Didn't work as expected

26 17%

Death

24 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause vocalising in dogs?: 156 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Buprenorphine 157 reports · 9.9% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with vocalising