Drooling after Buprenorphine in dogs

121 reports to the FDA describe drooling in dogs given Buprenorphine. That is 7.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

121Reports

68%Marked serious

27%Recovered

21%Died or euthanised

Same dayTypical onset

How soon it started

Same day

73 62%

1–2 days

12 10%

3–7 days

11 9.4%

1–4 weeks

7 6.0%

Over a month

14 12%

How the animals did

Recovered

32 26%

Recovered with lasting effects

1 0.8%

Still unwell when reported

54 45%

Died

11 9.1%

Euthanised

14 12%

Not known

9 7.4%

Problems reported at the same time

43 36%

41 34%

38 31%

34 28%

25 21%

23 19%

23 19%

17 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause drooling in dogs?: 121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drooling with similar medicines

Drooling after Dexmedetomidine (Dexdomitor) 164 reports · 3.0% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with drooling