Kidney problems after Buprenorphine in dogs

160 reports to the FDA describe kidney problems in dogs given Buprenorphine. That is 10% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

160Reports

90%Marked serious

7.5%Recovered

60%Died or euthanised

3 daysTypical onset

How soon it started

Same day

29 22%

1–2 days

34 25%

3–7 days

20 15%

1–4 weeks

32 24%

Over a month

19 14%

How the animals did

Recovered

12 7.5%

Still unwell when reported

38 24%

Died

28 18%

Euthanised

68 43%

Not known

14 8.8%

Problems reported at the same time

116 73%

107 67%

96 60%

91 57%

83 52%

57 36%

49 31%

49 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause kidney problems in dogs?: 160 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Dexmedetomidine (Dexdomitor) 184 reports · 3.4% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with kidney problems