Kidney problems after Dexmedetomidine (Dexdomitor) in dogs

184 reports to the FDA describe kidney problems in dogs given Dexmedetomidine. That is 3.4% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

184Reports

68%Marked serious

12%Recovered

48%Died or euthanised

3 daysTypical onset

How soon it started

Same day

35 26%

1–2 days

32 24%

3–7 days

27 20%

1–4 weeks

22 16%

Over a month

20 15%

How the animals did

Recovered

22 12%

Still unwell when reported

45 24%

Died

46 25%

Euthanised

42 23%

Not known

29 16%

Problems reported at the same time

107 58%

103 56%

93 51%

90 49%

87 47%

49 27%

42 23%

36 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause kidney problems in dogs?: 184 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Buprenorphine 160 reports · 10% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with kidney problems