Accidental exposure after Dexmedetomidine (Dexdomitor) in dogs

97 reports to the FDA describe accidental exposure in dogs given Dexmedetomidine. That is 1.8% of all reports for this medicine, compared with 1.5% across reports for all dog medicines.

97Reports

10%Marked serious

44%Recovered

0.0%Died or euthanised

Same dayTypical onset

How soon it started

Same day

19 90%

1–2 days

1 4.8%

3–7 days

0 0.0%

1–4 weeks

1 4.8%

Over a month

0 0.0%

How the animals did

Recovered

40 41%

Recovered with lasting effects

3 3.1%

Still unwell when reported

22 23%

Not known

32 33%

Problems reported at the same time

Overdose

83 86%

Locking mechanism abnormal

50 52%

Sedation

44 45%

Bradycardia

19 20%

Incorrect dose administered

13 13%

Lethargy

10 10%

Difficulty of use

10 10%

Pale mucous membrane

7 7.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause accidental exposure in dogs?: 97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with accidental exposure