Pale mucous membrane after Dexmedetomidine (Dexdomitor) in dogs

176 reports to the FDA describe pale mucous membrane in dogs given Dexmedetomidine. That is 3.2% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

176Reports
56%Marked serious
38%Recovered
29%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
94 70%
1–2 days
12 9.0%
3–7 days
6 4.5%
1–4 weeks
8 6.0%
Over a month
14 10%

How the animals did

Recovered
66 38%
Still unwell when reported
37 21%
Died
34 19%
Euthanised
17 9.7%
Not known
22 13%

Problems reported at the same time

Age of the animals

Under 1 year
41
1–3 years
34
4–7 years
34
8–11 years
41
12+ years
13

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause pale mucous membrane in dogs?
176 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with pale mucous membrane