Locking mechanism abnormal after Dexmedetomidine (Dexdomitor) in dogs

56 reports to the FDA describe locking mechanism abnormal in dogs given Dexmedetomidine. That is 1.0% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

56Reports

5.4%Marked serious

52%Recovered

0.0%Died or euthanised

–Typical onset

How the animals did

Recovered

27 48%

Recovered with lasting effects

2 3.6%

Still unwell when reported

1 1.8%

Not known

26 46%

Problems reported at the same time

53 95%

50 89%

21 38%

11 20%

7 13%

Device defective

6 11%

No sign

5 8.9%

Missing component, medical device

4 7.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause locking mechanism abnormal in dogs?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with locking mechanism abnormal