Liver problems after Denamarin in dogs

The FDA has received 122 reports of liver problems in dogs after Denamarin. That is 32% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

122Reports
80%Marked serious
4.1%Recovered
26%Died or euthanised
30 daysTypical onset
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How soon it started

Same day
12 12%
1–2 days
7 6.9%
3–7 days
9 8.8%
1–4 weeks
26 25%
Over a month
48 47%

How the animals did

Recovered
5 4.1%
Still unwell when reported
60 49%
Died
11 9.0%
Euthanised
21 17%
Not known
25 20%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
8
4–7 years
15
8–11 years
41
12+ years
55

About this medicine

Type: medicine.

Questions owners ask

Can Denamarin cause liver problems in dogs?
122 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 30 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Denamarin in dogs · Medicines most reported with liver problems