Fever after Cyclosporine (Atopica) in dogs

243 reports to the FDA describe fever in dogs given Cyclosporine. That is 1.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

243Reports

37%Marked serious

8.6%Recovered

27%Died or euthanised

20 daysTypical onset

How soon it started

Same day

8 11%

1–2 days

6 7.9%

3–7 days

16 21%

1–4 weeks

16 21%

Over a month

30 39%

How the animals did

Recovered

19 7.8%

Recovered with lasting effects

2 0.8%

Still unwell when reported

34 14%

Died

42 17%

Euthanised

23 9.5%

Not known

123 51%

Problems reported at the same time

134 55%

120 49%

83 34%

71 29%

66 27%

64 26%

60 25%

57 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause fever in dogs?: 243 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Oclacitinib (Apoquel) 516 reports · 1.8% of its reports
Fever after Ilunocitinib (Zenrelia) 79 reports · 3.6% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with fever