Dehydration after Cyclosporine (Atopica) in dogs

131 reports to the FDA describe dehydration in dogs given Cyclosporine. That is 0.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

131Reports

51%Marked serious

23%Recovered

23%Died or euthanised

17 daysTypical onset

How soon it started

Same day

9 16%

1–2 days

7 13%

3–7 days

7 13%

1–4 weeks

10 18%

Over a month

23 41%

How the animals did

Recovered

28 21%

Recovered with lasting effects

2 1.5%

Still unwell when reported

15 11%

Died

15 11%

Euthanised

15 11%

Not known

56 43%

Problems reported at the same time

93 71%

78 60%

73 56%

57 44%

46 35%

30 23%

29 22%

23 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause dehydration in dogs?: 131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Oclacitinib (Apoquel) 182 reports · 0.6% of its reports
Dehydration after Ilunocitinib (Zenrelia) 30 reports · 1.4% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with dehydration