Collapse after Cyclosporine (Atopica) in dogs

The FDA has received 179 reports of collapse in dogs after Cyclosporine. That is 1.2% of all reports for this medicine, compared with 0.9% across reports for all dog medicines.

179Reports

35%Marked serious

17%Recovered

17%Died or euthanised

20 daysTypical onset

How soon it started

Same day

12 24%

1–2 days

4 7.8%

3–7 days

4 7.8%

1–4 weeks

8 16%

Over a month

23 45%

How the animals did

Recovered

29 16%

Recovered with lasting effects

1 0.6%

Still unwell when reported

9 5.0%

Died

17 9.5%

Euthanised

13 7.3%

Not known

110 61%

Problems reported at the same time

88 49%

75 42%

52 29%

49 27%

49 27%

43 24%

37 21%

33 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause collapse in dogs?: 179 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

Collapse after Oclacitinib (Apoquel) 230 reports · 0.8% of its reports
Collapse after Ilunocitinib (Zenrelia) 25 reports · 1.1% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with collapse