Liver problems after Bravecto in dogs

The FDA has received 24 reports of liver problems in dogs after Bravecto. That is 12% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports
71%Marked serious
4.2%Recovered
17%Died or euthanised
47 daysTypical onset
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How soon it started

Same day
2 9.5%
1–2 days
3 14%
3–7 days
1 4.8%
1–4 weeks
3 14%
Over a month
12 57%

How the animals did

Recovered
1 4.2%
Still unwell when reported
19 79%
Died
2 8.3%
Euthanised
2 8.3%

Problems reported at the same time

Elevated symmetrical dimethylarginine (sdma)
5 21%
4 17%
Kidney problems
4 17%
Abnormal radiograph finding
4 17%
Blood problems
3 13%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
7
8–11 years
9
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Bravecto cause liver problems in dogs?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 47 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Bravecto in dogs · Medicines most reported with liver problems