Hyperphosphataemia after Ampicillin in dogs

85 reports to the FDA describe hyperphosphataemia in dogs given Ampicillin. That is 8.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

85Reports
92%Marked serious
8.2%Recovered
71%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
10 14%
1–2 days
14 19%
3–7 days
15 20%
1–4 weeks
23 31%
Over a month
12 16%

How the animals did

Recovered
7 8.2%
Still unwell when reported
14 16%
Died
21 25%
Euthanised
39 46%
Not known
4 4.7%

Problems reported at the same time

Age of the animals

Under 1 year
19
1–3 years
14
4–7 years
13
8–11 years
24
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause hyperphosphataemia in dogs?
85 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with hyperphosphataemia