Pain after Amoxicillin + Clavulanate (Clavamox) in dogs

130 reports to the FDA describe pain in dogs given Amoxicillin + Clavulanate. That is 2.4% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

130Reports
51%Marked serious
9.2%Recovered
25%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
15 17%
1–2 days
16 19%
3–7 days
13 15%
1–4 weeks
22 26%
Over a month
20 23%

How the animals did

Recovered
10 7.7%
Recovered with lasting effects
2 1.5%
Still unwell when reported
50 38%
Died
19 15%
Euthanised
13 10%
Not known
36 28%

Problems reported at the same time

Age of the animals

Under 1 year
21
1–3 years
17
4–7 years
28
8–11 years
39
12+ years
23

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause pain in dogs?
130 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with pain