Hyperglycaemia after Amoxicillin + Clavulanate (Clavamox) in dogs

100 reports to the FDA describe hyperglycaemia in dogs given Amoxicillin + Clavulanate. That is 1.9% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

100Reports
67%Marked serious
11%Recovered
32%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
11 17%
1–2 days
11 17%
3–7 days
12 18%
1–4 weeks
11 17%
Over a month
21 32%

How the animals did

Recovered
10 10%
Recovered with lasting effects
1 1.0%
Still unwell when reported
29 29%
Died
17 17%
Euthanised
15 15%
Not known
28 28%

Problems reported at the same time

Age of the animals

Under 1 year
11
1–3 years
8
4–7 years
26
8–11 years
32
12+ years
21

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause hyperglycaemia in dogs?
100 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperglycaemia with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with hyperglycaemia