Fever after Amoxicillin + Clavulanate (Clavamox) in dogs

342 reports to the FDA describe fever in dogs given Amoxicillin + Clavulanate. That is 6.4% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

342Reports
52%Marked serious
9.4%Recovered
23%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
29 13%
1–2 days
43 20%
3–7 days
46 21%
1–4 weeks
45 21%
Over a month
53 25%

How the animals did

Recovered
29 8.5%
Recovered with lasting effects
3 0.9%
Still unwell when reported
130 38%
Died
32 9.4%
Euthanised
45 13%
Not known
103 30%

Problems reported at the same time

Age of the animals

Under 1 year
61
1–3 years
74
4–7 years
77
8–11 years
87
12+ years
38

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause fever in dogs?
342 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with fever