Fever after Amoxicillin in dogs

The FDA has received 81 reports of fever in dogs after Amoxicillin. That is 6.0% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

81Reports

67%Marked serious

9.9%Recovered

33%Died or euthanised

5 daysTypical onset

How soon it started

Same day

6 12%

1–2 days

14 27%

3–7 days

11 21%

1–4 weeks

14 27%

Over a month

7 13%

How the animals did

Recovered

8 9.9%

Still unwell when reported

26 32%

Died

11 14%

Euthanised

16 20%

Not known

20 25%

Problems reported at the same time

49 60%

42 52%

32 40%

30 37%

27 33%

21 26%

20 25%

18 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause fever in dogs?: 81 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Amoxicillin + Clavulanate (Clavamox) 342 reports · 6.4% of its reports
Fever after Doxycycline 237 reports · 5.9% of its reports
Fever after Cefovecin (Convenia) 220 reports · 5.8% of its reports
Fever after Enrofloxacin (Baytril) 280 reports · 7.4% of its reports
Fever after Metronidazole 178 reports · 5.8% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with fever