Liver problems after Adequan in dogs

The FDA has received 40 reports of liver problems in dogs after Adequan. That is 10% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
73%Marked serious
7.5%Recovered
10%Died or euthanised
15 daysTypical onset
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How soon it started

Same day
6 19%
1–2 days
4 13%
3–7 days
1 3.2%
1–4 weeks
7 23%
Over a month
13 42%

How the animals did

Recovered
3 7.5%
Still unwell when reported
29 73%
Died
2 5.0%
Euthanised
2 5.0%
Not known
4 10%

Problems reported at the same time

11 28%
Elevated symmetrical dimethylarginine (sdma)
6 15%
Abnormal ultrasound finding
5 13%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
1
8–11 years
16
12+ years
23

About this medicine

Type: medicine.

Questions owners ask

Can Adequan cause liver problems in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 15 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Adequan in dogs · Medicines most reported with liver problems