Vocalising after Emodepside + Praziquantel (Profender) in cats

130 reports to the FDA describe vocalising in cats given Emodepside + Praziquantel. That is 2.3% of all reports for this medicine, compared with 3.1% across reports for all cat medicines.

130Reports
63%Marked serious
33%Recovered
17%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
57 55%
1–2 days
28 27%
3–7 days
11 11%
1–4 weeks
3 2.9%
Over a month
4 3.9%

How the animals did

Recovered
42 32%
Recovered with lasting effects
1 0.8%
Still unwell when reported
9 6.9%
Died
13 10%
Euthanised
9 6.9%
Not known
56 43%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
44
4–7 years
27
8–11 years
19
12+ years
15

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause vocalising in cats?
130 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with vocalising