Not drinking after Emodepside + Praziquantel (Profender) in cats

The FDA has received 34 reports of not drinking in cats after Emodepside + Praziquantel. That is 0.6% of all reports for this medicine, compared with 1.1% across reports for all cat medicines, so it is reported less often than average with this medicine.

34Reports

47%Marked serious

24%Recovered

12%Died or euthanised

1 daysTypical onset

How soon it started

Same day

7 23%

1–2 days

12 40%

3–7 days

5 17%

1–4 weeks

6 20%

Over a month

0 0.0%

How the animals did

Recovered

8 24%

Still unwell when reported

9 26%

Died

2 5.9%

Euthanised

2 5.9%

Not known

13 38%

Problems reported at the same time

32 94%

17 50%

10 29%

9 26%

6 18%

6 18%

5 15%

4 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause not drinking in cats?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with not drinking