Restlessness or agitation after Polysulfated Glycosaminoglycan in horses

The FDA has received 20 reports of restlessness or agitation in horses after Polysulfated Glycosaminoglycan. That is 3.9% of all reports for this medicine, compared with 2.6% across reports for all horse medicines.

20Reports
35%Marked serious
55%Recovered
0.0%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
4 40%
1–2 days
0 0.0%
3–7 days
1 10%
1–4 weeks
3 30%
Over a month
2 20%

How the animals did

Recovered
11 55%
Still unwell when reported
1 5.0%
Not known
8 40%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
2
8–11 years
2
12+ years
12

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause restlessness or agitation in horses?
20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in horses · Medicines most reported with restlessness or agitation