Restlessness or agitation after Xylazine in horses

The FDA has received 24 reports of restlessness or agitation in horses after Xylazine. That is 5.2% of all reports for this medicine, compared with 2.6% across reports for all horse medicines, so it is reported unusually often with this medicine.

24Reports
46%Marked serious
50%Recovered
8.3%Died or euthanised
–Typical onset
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How the animals did

Recovered
11 46%
Recovered with lasting effects
1 4.2%
Died
1 4.2%
Euthanised
1 4.2%
Not known
10 42%

Problems reported at the same time

Tachycardia
4 17%
3 13%
2 8.3%
Staggering
2 8.3%

Age of the animals

Under 1 year
1
1–3 years
9
4–7 years
1
8–11 years
0
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Xylazine cause restlessness or agitation in horses?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Xylazine in horses · Medicines most reported with restlessness or agitation