Xylazine side effects in horses

465 reports sent to the FDA between 1995 and 2026 involve Xylazine in horses. The most reported problems were collapse, seizures, breathing problems. 33% were marked serious, and where it was recorded, signs eased after stopping the medicine in 85% of cases.

465Reports
33%Marked serious
61%Only medicine involved
38%Recovered
16%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

42 9.0%
36 7.7%
20 4.3%
Swelling
17 3.7%
Recumbency
16 3.4%
Hyperexcitation
15 3.2%
Tachycardia
14 3.0%
Pale mucous membrane
12 2.6%
Nystagmus
11 2.4%
Fever
11 2.4%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
166 83%
1–2 days
17 8.5%
3–7 days
7 3.5%
1–4 weeks
4 2.0%
Over a month
5 2.5%

Time from the first dose to the first sign, where both dates were reported (199 reports).

How the animals did

Recovered
172 37%
Recovered with lasting effects
4 0.9%
Still unwell when reported
7 1.5%
Died
45 9.7%
Euthanised
30 6.5%
Not known
207 45%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for horses