Restlessness or agitation after Penicillin G Procaine in horses

The FDA has received 24 reports of restlessness or agitation in horses after Penicillin G Procaine. That is 30% of all reports for this medicine, compared with 2.6% across reports for all horse medicines, so it is reported unusually often with this medicine.

24Reports
8.3%Marked serious
8.3%Recovered
25%Died or euthanised
–Typical onset
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How the animals did

Recovered
2 8.3%
Died
6 25%
Not known
16 67%

Problems reported at the same time

6 25%
Collapse
6 25%
Disorientation
6 25%
Wobbliness (ataxia)
6 25%
Tremors
5 21%
Seizures
3 13%
Swelling
3 13%

Age of the animals

Under 1 year
2
1–3 years
6
4–7 years
2
8–11 years
3
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Penicillin G Procaine cause restlessness or agitation in horses?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Penicillin G Procaine in horses · Medicines most reported with restlessness or agitation