Swelling after Polysulfated Glycosaminoglycan in horses

The FDA has received 172 reports of swelling in horses after Polysulfated Glycosaminoglycan. That is 33% of all reports for this medicine, compared with 19% across reports for all horse medicines, so it is reported unusually often with this medicine.

172Reports
39%Marked serious
36%Recovered
0.0%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
24 23%
1–2 days
19 18%
3–7 days
14 13%
1–4 weeks
39 38%
Over a month
8 7.7%

How the animals did

Recovered
61 35%
Recovered with lasting effects
1 0.6%
Still unwell when reported
17 9.9%
Not known
93 54%

Problems reported at the same time

42 24%
17 9.9%
Abnormal ultrasound finding
15 8.7%
Stiffness
14 8.1%

Age of the animals

Under 1 year
0
1–3 years
14
4–7 years
38
8–11 years
30
12+ years
64

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause swelling in horses?
172 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in horses · Medicines most reported with swelling