Swelling after Pentosan Polysulfate Sodium in horses

73 reports to the FDA describe swelling in horses given Pentosan Polysulfate Sodium. That is 36% of all reports for this medicine, compared with 19% across reports for all horse medicines, so it is reported unusually often with this medicine.

73Reports
74%Marked serious
55%Recovered
0.0%Died or euthanised
1 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
19 26%
1–2 days
27 38%
3–7 days
9 13%
1–4 weeks
14 19%
Over a month
3 4.2%

How the animals did

Recovered
40 55%
Still unwell when reported
4 5.5%
Not known
29 40%

Problems reported at the same time

Reluctant to move
8 11%
Fever
5 6.8%
Muscle stiffness
5 6.8%
Lethargy
4 5.5%
Loss of appetite
4 5.5%
Stiffness
3 4.1%
Irritability
3 4.1%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
10
8–11 years
19
12+ years
30

About this medicine

Type: medicine.

Questions owners ask

Can Pentosan Polysulfate Sodium cause swelling in horses?
73 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Pentosan Polysulfate Sodium in horses · Medicines most reported with swelling