Pentosan Polysulfate Sodium side effects in horses

203 reports sent to the FDA between 2023 and 2026 involve Pentosan Polysulfate Sodium in horses. The most reported problems were injection site reaction, swelling, allergic reaction. 55% were marked serious, and where it was recorded, signs eased after stopping the medicine in 93% of cases.

203Reports
55%Marked serious
82%Only medicine involved
49%Recovered
1.0%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

73 36%
20 9.9%
Itching
16 7.9%
Colic
14 6.9%
Reluctant to move
13 6.4%
Loss of appetite
12 5.9%
Behaviour change
11 5.4%
Lethargy
11 5.4%
Restlessness or agitation
10 4.9%
Muscle stiffness
9 4.4%
Pawing
8 3.9%
Fever
8 3.9%
Lying down
7 3.4%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.

Didn't work as expected
2 1.0%

How soon problems started

Same day
63 32%
1–2 days
41 21%
3–7 days
23 12%
1–4 weeks
35 18%
Over a month
32 16%

Time from the first dose to the first sign, where both dates were reported (194 reports).

How the animals did

Recovered
97 48%
Recovered with lasting effects
2 1.0%
Still unwell when reported
11 5.4%
Died
2 1.0%
Not known
91 45%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for horses