Injection site reaction after Polysulfated Glycosaminoglycan in horses

152 reports to the FDA describe injection site reaction in horses given Polysulfated Glycosaminoglycan. That is 29% of all reports for this medicine, compared with 6.2% across reports for all horse medicines, so it is reported unusually often with this medicine.

152Reports
35%Marked serious
36%Recovered
0.7%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
28 26%
1–2 days
16 15%
3–7 days
12 11%
1–4 weeks
37 35%
Over a month
13 12%

How the animals did

Recovered
53 35%
Recovered with lasting effects
1 0.7%
Still unwell when reported
15 9.9%
Euthanised
1 0.7%
Not known
82 54%

Problems reported at the same time

76 50%
37 24%
15 9.9%
Abnormal ultrasound finding
15 9.9%
Stiffness
10 6.6%

Age of the animals

Under 1 year
0
1–3 years
12
4–7 years
27
8–11 years
31
12+ years
54

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause injection site reaction in horses?
152 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in horses · Medicines most reported with injection site reaction