Injection site reaction after Clodronate Disodium in horses

31 reports to the FDA describe injection site reaction in horses given Clodronate Disodium. That is 10% of all reports for this medicine, compared with 6.2% across reports for all horse medicines, so it is reported unusually often with this medicine.

31Reports
58%Marked serious
58%Recovered
3.2%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
11 48%
1–2 days
5 22%
3–7 days
2 8.7%
1–4 weeks
4 17%
Over a month
1 4.3%

How the animals did

Recovered
17 55%
Recovered with lasting effects
1 3.2%
Still unwell when reported
1 3.2%
Euthanised
1 3.2%
Not known
11 35%

Problems reported at the same time

Fever
5 16%
Recumbency
3 9.7%
3 9.7%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
4
8–11 years
10
12+ years
13

About this medicine

Type: medicine.

Questions owners ask

Can Clodronate Disodium cause injection site reaction in horses?
31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Clodronate Disodium in horses · Medicines most reported with injection site reaction