Excessive thirst after Clodronate Disodium in horses

62 reports to the FDA describe excessive thirst in horses given Clodronate Disodium. That is 20% of all reports for this medicine, compared with 0.7% across reports for all horse medicines, so it is reported unusually often with this medicine.

62Reports

77%Marked serious

44%Recovered

3.2%Died or euthanised

1 daysTypical onset

How soon it started

Same day

9 21%

1–2 days

21 50%

3–7 days

6 14%

1–4 weeks

4 9.5%

Over a month

2 4.8%

How the animals did

Recovered

26 42%

Recovered with lasting effects

1 1.6%

Still unwell when reported

2 3.2%

Euthanised

2 3.2%

Not known

31 50%

Problems reported at the same time

58 94%

47 76%

29 47%

19 31%

15 24%

13 21%

11 18%

9 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Clodronate Disodium cause excessive thirst in horses?: 62 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Flunixin Meglumine 20 reports · 3.2% of its reports

All reported side effects of Clodronate Disodium in horses · Medicines most reported with excessive thirst