Injection site reaction after Ceftiofur in horses

The FDA has received 470 reports of injection site reaction in horses after Ceftiofur. That is 39% of all reports for this medicine, compared with 6.2% across reports for all horse medicines, so it is reported unusually often with this medicine.

470Reports
37%Marked serious
36%Recovered
3.6%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
70 19%
1–2 days
104 28%
3–7 days
146 39%
1–4 weeks
41 11%
Over a month
13 3.5%

How the animals did

Recovered
150 32%
Recovered with lasting effects
19 4.0%
Still unwell when reported
132 28%
Died
9 1.9%
Euthanised
8 1.7%
Not known
152 32%

Problems reported at the same time

Age of the animals

Under 1 year
15
1–3 years
51
4–7 years
65
8–11 years
76
12+ years
198

About this medicine

Type: medicine.

Questions owners ask

Can Ceftiofur cause injection site reaction in horses?
470 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Ceftiofur in horses · Medicines most reported with injection site reaction