Hair coat discolouration after Polysulfated Glycosaminoglycan in horses

The FDA has received 33 reports of hair coat discolouration in horses after Polysulfated Glycosaminoglycan. That is 6.4% of all reports for this medicine, compared with 0.3% across reports for all horse medicines, so it is reported unusually often with this medicine.

33Reports

3.0%Marked serious

18%Recovered

0.0%Died or euthanised

15 daysTypical onset

How soon it started

Same day

11 39%

1–2 days

0 0.0%

3–7 days

1 3.6%

1–4 weeks

9 32%

Over a month

7 25%

How the animals did

Recovered

6 18%

Not known

27 82%

Problems reported at the same time

Injection site reaction

24 73%

Swelling

3 9.1%

Product defect, general

3 9.1%

Inappropriate schedule of drug administration

3 9.1%

Lethargy

2 6.1%

Pain

2 6.1%

Hair loss

2 6.1%

Application site reaction

1 3.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause hair coat discolouration in horses?: 33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Polysulfated Glycosaminoglycan in horses · Medicines most reported with hair coat discolouration